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Increased thermogenesis in fat cells during active period of circadian rhythm limits weight gain in mice

A team of researchers at Northwestern University, working with a pair of colleagues from the University of Texas, has found that an increase in thermogenesis in fat cells during active periods of the daily circadian rhythm can limit weight gain... Continue Reading →

The fountain of life: Water droplets hold the secret ingredient for building life

Purdue University chemists have uncovered a mechanism for peptide-forming reactions to occur in water — something that has puzzled scientists for decades. “This is essentially the chemistry behind the origin of life,” said Graham Cooks, the Henry Bohn Hass Distinguished Professor... Continue Reading →

Harvard team detects first definitive proof of sea level fingerprints from melting of glacial ice sheets

When glacial ice sheets melt, something counterintuitive happens to sea levels. Logic might suggest that nearby levels would rise, but instead they fall. Thousands of miles away, however, they do go up in a kind of seesaw effect. Why? The... Continue Reading →

Beyond AlphaFold: A.I. excels at creating new proteins

Over the past two years, machine learning has revolutionized protein structure prediction. Now, three papers in Science describe a similar revolution in protein design. In the new papers, biologists at the University of Washington School of Medicine show that machine learning can... Continue Reading →

A new study has concluded that there is no clear evidence that COVID-19 was transmitted from bats

A new Tel Aviv University study rejects assertions, according to which the origin of the COVID-19 outbreak is in bats. According to the study, bats have a highly effective immune system that enables them to deal relatively easily with viruses... Continue Reading →

Synthetic” mouse embryo with brain and beating heart grown from stem cells

Researchers from the University of Cambridge and Caltech have created model mouse embryos from stem cells—the body's master cells, which can develop into almost any cell type in the body—that have beating hearts, as well as the foundations for a... Continue Reading →

A major step forward for organ biofabrication

By recreating the helical structure of heart muscles, researchers improve understanding of how the heart beats Heart disease — the leading cause of death in the U.S. — is so deadly in part because the heart, unlike other organs, cannot... Continue Reading →

New research may explain unexpected effects of common painkillers

Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and aspirin are widely used to treat pain and inflammation. But even at similar doses, different NSAIDs can have unexpected and unexplained effects on many diseases, including heart disease and cancer. Now, a... Continue Reading →

Old skins cells reprogrammed to regain youthful function

Research from the Babraham Institute has developed a method to 'time jump' human skin cells by 30 years, turning back the ageing clock for cells without losing their specialised function. Work by researchers in the Institute's Epigenetics research programme has... Continue Reading →

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